Liver Cancer

Liver cancer is a tumor that first develops in the liver tissue. Different types of liver cancer exist in the form of cancer cells. According to our liver cancer specialist in Kolkata hepatocellular carcinoma is the most common type of liver cancer. About 90% of all liver cancers. Hepatocellular carcinoma begins in the hepatocytes, the major cells in the liver. Liver cancer represents the 6th most common cancer in the world. It is most common in South-East Asia and West Africa. This is mainly because hepatitis B infection increases the risk of liver cancer and is more common in these areas. In the USA and Southern Europe, the hepatitis C virus * is often identified as the cause of liver cancer. The average age of diagnosis is from 50-60 years, but in Asia and Africa it is usually from 40-50 years.

Cause:

In many patients, liver cancer is preceded by cirrhosis of the liver. Cirrhosis of liver is the result of chronic liver disease, but only a limited percentage of people with chronic liver disease will eventually develop it with cirrhosis of the liver.

The exact mechanisms and causes of liver cancer are not fully understood. However, cirrhosis and its causes are the leading causes of hepatocellular carcinoma, a major type of liver cancer.

What our patients say

Causes of liver cirrhosis:

  • Chronic infection with hepatitis-B virus (HBV) or hepatitis-C virus (HCV)
  • Excessive drinking
  • Other inherited genetic conditions can also cause cirrhosis, such as haemochromatosis or alpha-1-antitrypsin
  • Non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

There are other, more common, medical conditions that affect the liver and increase the risk of cancer, says the best liver cancer doctor in Kolkata. These conditions include autoimmune hepatitis, intrahepatic biliary inflammations (primary biliary cirrhosis and primary sclerosing cholangitis) and Wilson’s disease.

Exposure to toxic drugs:

  • Anabolic steroids
  • Food contaminated with Aflatoxin

Diagnosis:

Most patients have cirrhosis of the liver and / or chronic hepatitis before developing liver cancer. People with cirrhosis of the liver need close monitoring to quickly detect a potential liver tumor.

The same treatment is recommended for people with HBV who have never had cirrhosis and for whom more than 10,000 copies of the virus (viral load) are obtained per milliliter of blood, and for people infected with HCV with high-grade liver fibrosis.

 Tissue Monitoring:

  • Ultrasound examination (used to detect nodules)
  • Blood test (a protein called alpha-fetoprotein, or AFP)
  • Possible Symptoms of Liver Cancer:
  • Unexplained weight loss
  • Fatigue
  • Loss of appetite or feeling very full after a small meal
  • Nausea or vomiting
  • Fever
  • Increased courage
  • Pain in the abdomen or near the right shoulder
  • Itching
  • Yellow skin and eyes (jaundice)

Liver Cancer Treatment Options in Kolkata:

Treatment planning involves a multidisciplinary team of medical professionals. The duration of treatment will depend on the stage of the cancer, the tumor structures and the risks involved.

The top three options in these categories are:

  • Surgical resection of the tumor
  • Liver transplantation
  • Local extraction methods

Reconstructive surgery: Surgical resection of the tumor is the preferred method for patients who do not have cirrhosis of the liver and who do not have enough liver storage; patients with BCLC stage 0 or A in their operating condition that allows them to have surgery and have a single liver tumor that does not cause high blood pressure at the site.

Liver transplantation: If transplantation is not possible, liver transplantation should be considered whether there is a single tumor less than 5 cm wide, or where there are 2 to 3 plants, each less than 3 cm wide. Those needs are called Milan policies.

Removal methods: The purpose of local removal * is to destroy cancer cells by directing them chemically or physically. The two main methods of local financing are radio frequency ablation (RFA) and short-term ethanol injection.

While these methods work to destroy small tissues, they unfortunately do not prevent the emergence of new lesions in the cirrhotic liver tissue.

They have been prioritized as an alternative to surgery. In patients with stage 0 BCLC and who can be resuscitated with surgery or liver transplantation, these methods are recommended. They are also recommended in the case of a long-awaited wait (> 6 months) for liver transplantation.

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